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Downregulation of key regulatory proteins in androgen dependent prostate tumor cells by oncolytic reovirus
As prostate tumor cell growth depends on hormones, androgen ablation is an effective therapy for prostate cancer (PCa). However, progression of PCa cells to androgen independent growth (castrate resistant prostate cancer, CRPC) results in relapse and mortality. Hypoxia, a microenvironment of low oxy...
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Publicado no: | Virology |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4619118/ https://ncbi.nlm.nih.gov/pubmed/26264969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.07.007 |
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