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Downregulation of key regulatory proteins in androgen dependent prostate tumor cells by oncolytic reovirus

As prostate tumor cell growth depends on hormones, androgen ablation is an effective therapy for prostate cancer (PCa). However, progression of PCa cells to androgen independent growth (castrate resistant prostate cancer, CRPC) results in relapse and mortality. Hypoxia, a microenvironment of low oxy...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Gupta-Saraf, Pooja, Meseke, Tyler, Miller, Cathy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619118/
https://ncbi.nlm.nih.gov/pubmed/26264969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.07.007
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