Co-Expression of Plexin-B1 and Met in Human Breast and Ovary Tumours Enhances the Risk of Progression

Background: Plex-B1, the receptor of Sema4D, has been implicated in tumour growth, angiogenesis and metastasis. The binding of Sema4D to Plex-B1 can trigger the activation of Met tyrosine kinase, thereby promoting cell dissociation and invasive growth. We tested the hypothesis that the expression of...

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Publicado en:Cell Oncol
Autores principales: Valente, Guido, Nicotra, Giuseppina, Arrondini, Marisa, Castino, Roberta, Capparuccia, Lorena, Prat, Maria, Kerim, Simonetta, Tamagnone, Luca, Isidoro, Ciro
Formato: Artigo
Lenguaje:Inglês
Publicado: IOS Press 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619042/
https://ncbi.nlm.nih.gov/pubmed/19940359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2009-0504
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