Bevacizumab and Combination Chemotherapy in rectal cancer Until Surgery (BACCHUS): a phase II, multicentre, open-label, randomised study of neoadjuvant chemotherapy alone in patients with high-risk cancer of the rectum

BACKGROUND: In locally advanced rectal cancer (LARC) preoperative chemoradiation (CRT) is the standard of care, but the risk of local recurrence is low with good quality total mesorectal excision (TME), although many still develop metastatic disease. Current challenges in treating rectal cancer incl...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Glynne-Jones, R., Hava, N., Goh, V., Bosompem, S., Bridgewater, J., Chau, I., Gaya, A., Wasan, H., Moran, B., Melcher, L., MacDonald, A., Osborne, M., Beare, S., Jitlal, M., Lopes, A., Hall, M., West, N., Quirke, P., Wong, Wai-Lup, Harrison, M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Study Protocol
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619031/
https://ncbi.nlm.nih.gov/pubmed/26493588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1764-1
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