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MicroRNA-17-5p induces drug resistance and invasion of ovarian carcinoma cells by targeting PTEN signaling

BACKGROUND: The miR-17-5p was overexpressed in ovarian cancer cells, and those cells were treated with paclitaxel. The proliferation of ovarian cancer cells was assessed by MTT assay. The Caspase-Glo3/7 and TUNEL assay were used to examine the effect of miR-17-5p on paclitaxel-induced apoptosis in o...

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Bibliografiske detaljer
Udgivet i:J Biol Res (Thessalon)
Main Authors: Fang, Ying, Xu, Changyan, Fu, Yan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619013/
https://ncbi.nlm.nih.gov/pubmed/26500892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40709-015-0035-2
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