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Karyotype alteration generates the neoplastic phenotypes of SV40-infected human and rodent cells
BACKGROUND: Despite over 50 years of research, it remains unclear how the DNA tumor viruses SV40 and Polyoma cause cancers. Prevailing theories hold that virus-coded Tumor (T)-antigens cause cancer by inactivating cellular tumor suppressor genes. But these theories don’t explain four characteristics...
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| 發表在: | Mol Cytogenet |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4618876/ https://ncbi.nlm.nih.gov/pubmed/26500699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-015-0183-y |
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