Single-Cell Analyses of ESCs Reveal Alternative Pluripotent Cell States and Molecular Mechanisms that Control Self-Renewal

Analyses of gene expression in single mouse embryonic stem cells (mESCs) cultured in serum and LIF revealed the presence of two distinct cell subpopulations with individual gene expression signatures. Comparisons with published data revealed that cells in the first subpopulation are phenotypically s...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Papatsenko, Dmitri, Darr, Henia, Kulakovskiy, Ivan V., Waghray, Avinash, Makeev, Vsevolod J., MacArthur, Ben D., Lemischka, Ihor R.
Format: Artigo
Language:Inglês
Published: Elsevier 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618835/
https://ncbi.nlm.nih.gov/pubmed/26267829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.07.004
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