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Single-Cell Analyses of ESCs Reveal Alternative Pluripotent Cell States and Molecular Mechanisms that Control Self-Renewal

Analyses of gene expression in single mouse embryonic stem cells (mESCs) cultured in serum and LIF revealed the presence of two distinct cell subpopulations with individual gene expression signatures. Comparisons with published data revealed that cells in the first subpopulation are phenotypically s...

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Bibliografische gegevens
Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Papatsenko, Dmitri, Darr, Henia, Kulakovskiy, Ivan V., Waghray, Avinash, Makeev, Vsevolod J., MacArthur, Ben D., Lemischka, Ihor R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618835/
https://ncbi.nlm.nih.gov/pubmed/26267829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.07.004
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