Presence of a High Amount of Stroma and Downregulation of SMAD4 Predict for Worse Survival for Stage I–II Colon Cancer Patients

Background: For stage I–II colon cancer a significant number (5–25%) of patients has recurrent disease within 5 years. There is need to identify these high-risk patients as they might benefit from additional treatment. Stroma-tissue surrounding the cancer cells plays an important role in the tumor b...

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Vydáno v:Cell Oncol
Hlavní autoři: Mesker, Wilma E., Liefers, Gerrit-Jan, Junggeburt, Jan M. C., van Pelt, Gabi W., Alberici, Paola, Kuppen, Peter J. K., Miranda, Noel F., van Leeuwen, Karin A. M., Morreau, Hans, Szuhai, Karoly, Tollenaar, Rob A. E. M., Tanke, Hans J.
Médium: Artigo
Jazyk:Inglês
Vydáno: IOS Press 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618830/
https://ncbi.nlm.nih.gov/pubmed/19478385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2009-0478
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