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Tegaserod mimics the neurostimulatory glycan polysialic acid and promotes nervous system repair

Glycans attached to the cell surface via proteins or lipids or exposed in the extracellular matrix affect many cellular processes, including neuritogenesis, cell survival and migration, as well as synaptic activity and plasticity. These functions make glycans attractive molecules for stimulating rep...

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Bibliographische Detailangaben
Veröffentlicht in:Neuropharmacology
Hauptverfasser: Bushman, J., Mishra, B., Ezra, M., Gul, S., Schulze, C., Chaudhury, S., Ripoll, D., Wallqvist, A., Kohn, J., Schachner, M., Loers, G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618794/
https://ncbi.nlm.nih.gov/pubmed/24067923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.09.014
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