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Identification and analysis of the bacterial endosymbiont specialized for production of the chemotherapeutic natural product ET-743

Ecteinascidin 743 (ET-743, Yondelis) is a clinically approved chemotherapeutic natural product isolated from the Caribbean mangrove tunicate Ecteinascidia turbinata. Researchers have long suspected that a microorganism may be the true producer of the anti-cancer drug, but its genome has remained elu...

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Detalhes bibliográficos
Publicado no:Environ Microbiol
Main Authors: Schofield, Michael M., Jain, Sunit, Porat, Daphne, Dick, Gregory J., Sherman, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618771/
https://ncbi.nlm.nih.gov/pubmed/26013440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1462-2920.12908
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