Systems analysis of non-parenchymal cell modulation of liver repair across multiple regeneration modes

BACKGROUND: A hallmark of chronic liver disease is the impairment of the liver’s innate regenerative ability. In this work we use a computational approach to unravel the principles underlying control of liver repair following an acute physiological challenge. METHODS: We used a mathematical model of...

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Udgivet i:BMC Syst Biol
Main Authors: Cook, Daniel, Ogunnaike, Babatunde A., Vadigepalli, Rajanikanth
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618752/
https://ncbi.nlm.nih.gov/pubmed/26493454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0220-9
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