Deficiency of HIF1alpha in antigen-presenting cells aggravates atherosclerosis and type 1 T helper cell responses in mice

OBJECTIVE: Although immune responses drive the pathogenesis of atherosclerosis, mechanisms that control antigen-presenting cell (APC)-mediated immune activation in atherosclerosis remain elusive. We here investigated the function of hypoxia-inducible factor (HIF)-1α in antigen presenting cells in at...

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Publicado no:Arterioscler Thromb Vasc Biol
Principais autores: Chaudhari, Sweena M., Sluimer, Judith C., Koch, Miriam, Theelen, Thomas L., Manthey, Helga D., Busch, Martin, Caballero-Franco, Celia, Vogel, Frederick, Cochain, Clement, Pelisek, Jaroslav, Daemen, Mat J., Lutz, Manfred B., Görlach, Agnes, Kissler, Stephan, Hermanns, Heike M., Zernecke, Alma
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618712/
https://ncbi.nlm.nih.gov/pubmed/26404487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306171
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