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Synthesis of F-18 labeled resazurin by direct electrophilic fluorination

We present the synthesis and characterization of F18-labeled fluorinated derivatives of resazurin, a probe for cell viability. The compounds were prepared by direct fluorination of resazurin with diluted [F18]-F(2) gas under acidic conditions. The fluorination occurs into the ortho-positions to the...

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Vydáno v:J Fluor Chem
Hlavní autoři: Kachur, Alexander V., Arroyo, Alejandro D., Popov, Anatoliy V., Saylor, Sarah J., Delikatny, E. James
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618668/
https://ncbi.nlm.nih.gov/pubmed/26504251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jfluchem.2015.07.017
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