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α-5 Laminin Synthesized by Human Pluripotent Stem Cells Promotes Self-Renewal

Substrate composition significantly impacts human pluripotent stem cell (hPSC) self-renewal and differentiation, but relatively little is known about the role of endogenously produced extracellular matrix (ECM) components in regulating hPSC fates. Here we identify α-5 laminin as a signature ECM comp...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Laperle, Alex, Hsiao, Cheston, Lampe, Michael, Mortier, Jaime, Saha, Krishanu, Palecek, Sean P., Masters, Kristyn S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618661/
https://ncbi.nlm.nih.gov/pubmed/26235893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.06.009
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