Maackiain is a novel antiallergic compound that suppresses transcriptional upregulation of the histamine H(1) receptor and interleukin-4 genes

Kujin contains antiallergic compounds that inhibit upregulation of histamine H(1) receptor (H1R) and interleukin (IL)-4 gene expression. However, the underlying mechanism remains unknown. We sought to identify a Kujin-derived antiallergic compound and investigate its mechanism of action. The H1R and...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Mizuguchi, Hiroyuki, Nariai, Yuki, Kato, Shuhei, Nakano, Tomohiro, Kanayama, Tomoyo, Kashiwada, Yoshiki, Nemoto, Hisao, Kawazoe, Kazuyoshi, Takaishi, Yoshihisa, Kitamura, Yoshiaki, Takeda, Noriaki, Fukui, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618638/
https://ncbi.nlm.nih.gov/pubmed/26516579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.166
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