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A Long-Lived Luminal Subpopulation Enriched with Alveolar Progenitors Serves as Cellular Origin of Heterogeneous Mammary Tumors

It has been shown that the mammary luminal lineage could be maintained by luminal stem cells or long-lived progenitors, but their identity and role in breast cancer remain largely elusive. By lineage analysis using Wap-Cre mice, we found that, in nulliparous females, mammary epithelial cells (MECs)...

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Udgivet i:Stem Cell Reports
Main Authors: Tao, Luwei, van Bragt, Maaike P.A., Li, Zhe
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618443/
https://ncbi.nlm.nih.gov/pubmed/26120057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.05.014
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