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Excretion Profiles and Half-Lives of Ten Urinary Polycyclic Aromatic Hydrocarbon Metabolites after Dietary Exposure

Human exposure to polycyclic aromatic hydrocarbons (PAHs) can be assessed by biomonitoring of their urinary mono-hydroxylated metabolites (OH-PAHs). Limited information exists on the human pharmacokinetics of OH-PAHs. This study aimed to investigate the excretion half-life of 1-hydroxypyrene (1-PYR)...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Li, Zheng, Romanoff, Lovisa, Bartell, Scott, Pittman, Erin N., Trinidad, Debra A., McClean, Michael, Webster, Thomas F., Sjödin, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618384/
https://ncbi.nlm.nih.gov/pubmed/22663094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300108e
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