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Comparison of multiple enzyme activatable near infrared fluorescent molecular probes for detection and quantification of inflammation in murine colitis models

BACKGROUND: Activatable near-infrared fluorescent (NIRF) probes have been used for ex vivo and in vivo detection of intestinal tumors in animal models. We hypothesized that NIRF probes activatable by cathepsins or MMPs will detect and quantify dextran sulphate sodium (DSS) induced acute colonic infl...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Ding, Shengli, Blue, Randal E., Morgan, Douglas R., Lund, Pauline K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618379/
https://ncbi.nlm.nih.gov/pubmed/24374874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.MIB.0000440612.98950.79
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