Evaluation of BRCA1-related molecular features and microRNAs as prognostic factors for triple negative breast cancers

BACKGROUND: The BRCA1 gene plays a key role in triple negative breast cancers (TNBCs), in which its expression can be lost by multiple mechanisms: germinal mutation followed by deletion of the second allele; negative regulation by promoter methylation; or miRNA-mediated silencing. This study aimed t...

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Библиографические подробности
Опубликовано в: :BMC Cancer
Главные авторы: Boukerroucha, Meriem, Josse, Claire, ElGuendi, Sonia, Boujemla, Bouchra, Frères, Pierre, Marée, Raphaël, Wenric, Stephane, Segers, Karin, Collignon, Joelle, Jerusalem, Guy, Bours, Vincent
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618357/
https://ncbi.nlm.nih.gov/pubmed/26490435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1740-9
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