Fanconi anemia mesenchymal stromal cells-derived glycerophospholipids skew hematopoietic stem cell differentiation through Toll-like receptor signaling

Fanconi anemia (FA) patients develop bone marrow (BM) failure or leukemia. One standard care for these devastating complications is hematopoietic stem cell transplantation. We identified a group of mesenchymal stromal cells (MSCs)-derived metabolites, glycerophospholipids and their endogenous inhibi...

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Bibliografiset tiedot
Julkaisussa:Stem Cells
Päätekijät: Amarachintha, Surya, Sertorio, Mathieu, Wilson, Andrew, Li, Xiaoli, Pang, Qishen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618082/
https://ncbi.nlm.nih.gov/pubmed/26212365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2100
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