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Stem cells in genetically-engineered mouse models of prostate cancer

The cancer stem cell model proposes that tumors have a hierarchical organization in which tumorigenic cells give rise to non-tumorigenic cells, with only a subset of stem-like cells able to propagate the tumor. In the case of prostate cancer, recent analyses of genetically engineered mouse (GEM) mod...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Shibata, Maho, Shen, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618022/
https://ncbi.nlm.nih.gov/pubmed/26341780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-15-0367
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