Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network

BACKGROUND: The reconstruction of context-specific metabolic models from easily and reliably measurable features such as transcriptomics data will be increasingly important in research and medicine. Current reconstruction methods suffer from high computational effort and arbitrary threshold setting....

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Pacheco, Maria Pires, John, Elisabeth, Kaoma, Tony, Heinäniemi, Merja, Nicot, Nathalie, Vallar, Laurent, Bueb, Jean-Luc, Sinkkonen, Lasse, Sauter, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617894/
https://ncbi.nlm.nih.gov/pubmed/26480823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1984-4
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