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New Supercharging Reagents Produce Highly Charged Protein Ions in Native Mass Spectrometry

The effectiveness of two new supercharging reagents for producing highly charged ions by electrospray ionization (ESI) from aqueous solutions in which proteins have native structures and reactivities were investigated. In aqueous solution, 2-thiophenone and 4-hydroxymethyl-1,3-dioxolan-2-one (HD) at...

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Détails bibliographiques
Publié dans:Analyst
Auteurs principaux: Going, Catherine C., Xia, Zijie, Williams, Evan R.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617834/
https://ncbi.nlm.nih.gov/pubmed/26421324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5an01710f
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