Controlled Dual Delivery of Fibroblast Growth Factor-2 and Interleukin-10 by Heparin-based Coacervate Synergistically Enhances Ischemic Heart Repair

Myocardial infarction (MI) causes myocardial necrosis, triggers chronic inflammatory responses, and leads to pathological remodeling. Controlled delivery of a combination of angiogenic and immunoregulatory proteins may be a promising therapeutic approach for MI. We investigated the bioactivity and t...

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Опубликовано в: :Biomaterials
Главные авторы: Chen, William C.W., Lee, Brandon G., Park, Dae Woo, Kim, Kyobum, Chu, Hunghao, Kim, Kang, Huard, Johnny, Wang, Yadong
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617784/
https://ncbi.nlm.nih.gov/pubmed/26370927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.08.050
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