Multispectral imaging of formalin-fixed tissue predicts ability to generate tumor-infiltrating lymphocytes from melanoma

BACKGROUND: Adoptive T cell therapy (ACT) has shown great promise in melanoma, with over 50 % response rate in patients where autologous tumor-reactive tumor-infiltrating lymphocytes (TIL) can be cultured and expanded. A major limitation of ACT is the inability to generate or expand autologous tumor...

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Publicat a:J Immunother Cancer
Autors principals: Feng, Zipei, Puri, Sachin, Moudgil, Tarsem, Wood, William, Hoyt, Clifford C., Wang, Chichung, Urba, Walter J., Curti, Brendan D., Bifulco, Carlo B., Fox, Bernard A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617712/
https://ncbi.nlm.nih.gov/pubmed/26500776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-015-0091-z
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