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Fine mapping of QTL and genomic prediction using allele-specific expression SNPs demonstrates that the complex trait of genetic resistance to Marek’s disease is predominantly determined by transcriptional regulation

BACKGROUND: Marek’s disease (MD) is a lymphoproliferative disease of poultry induced by Marek’s disease virus (MDV), a highly oncogenic alphaherpesvirus. Identifying the underlying genes conferring MD genetic resistance is desired for more efficacious control measures including genomic selection, wh...

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Foilsithe in:BMC Genomics
Main Authors: Cheng, Hans H., Perumbakkam, Sudeep, Pyrkosz, Alexis Black, Dunn, John R., Legarra, Andres, Muir, William M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617451/
https://ncbi.nlm.nih.gov/pubmed/26481588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2016-0
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