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Lxr-driven enterocyte lipid droplet formation delays transport of ingested lipids
Liver X receptors (Lxrs) are master regulators of cholesterol catabolism, driving the elimination of cholesterol from the periphery to the lumen of the intestine. Development of pharmacological agents to activate Lxrs has been hindered by synthetic Lxr agonists’ induction of hepatic lipogenesis and...
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| Publicat a: | J Lipid Res |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Biochemistry and Molecular Biology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617358/ https://ncbi.nlm.nih.gov/pubmed/25030662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M052845 |
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