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Ketone body therapy: from the ketogenic diet to the oral administration of ketone ester

Ketone bodies (KBs), acetoacetate and β-hydroxybutyrate (βHB), were considered harmful metabolic by-products when discovered in the mid-19th century in the urine of patients with diabetic ketoacidosis. It took physicians many years to realize that KBs are normal metabolites synthesized by the liver...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Lipid Res
Hauptverfasser: Hashim, Sami A., VanItallie, Theodore B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617348/
https://ncbi.nlm.nih.gov/pubmed/24598140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R046599
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