Miniature Swine as a Clinically Relevant Model of Graft-Versus-Host Disease

Miniature swine provide a preclinical model of hematopoietic cell transplantation (HCT) for studies of graft-versus-host disease. HCT between MHC-matched or ‑mismatched pigs can be performed to mimic clinical scenarios with outcomes that closely resemble those observed in human HCT recipients. With...

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Detalhes bibliográficos
Publicado no:Comp Med
Main Authors: Duran-Struuck, Raimon, Huang, Christene A, Orf, Katherine, Bronson, Roderick T, Sachs, David H, Spitzer, Thomas R
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Laboratory Animal Science 2015
Assuntos:
Swine Models
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617335/
https://ncbi.nlm.nih.gov/pubmed/26473348
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