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Interrogation of Multidrug Resistance (MDR1) P-glycoprotein (Pgp, ABCB1) Expression in Human Pancreatic Carcinoma Cells: Correlation of (99m)Tc-Sestamibi Uptake with Western Blot Analysis
OBJECTIVE: Histopathological studies indicate approximately 63% of pancreatic tumors express MDR1 Pgp and its polymorphic variants. However, Pgp expression detected at the messenger RNA or protein level does not always correlate with functional transport activity. Because Pgp transport activity is a...
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| Publicado no: | Nucl Med Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617235/ https://ncbi.nlm.nih.gov/pubmed/25036383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MNM.0000000000000158 |
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