Adiposity significantly modifies genetic risk for dyslipidemia

Recent genome-wide association studies have identified multiple loci robustly associated with plasma lipids, which also contribute to extreme lipid phenotypes. However, these common genetic variants explain <12% of variation in lipid traits. Adiposity is also an important determinant of plasma li...

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Библиографические подробности
Опубликовано в: :J Lipid Res
Главные авторы: Cole, Christopher B., Nikpay, Majid, Lau, Paulina, Stewart, Alexandre F. R., Davies, Robert W., Wells, George A., Dent, Robert, McPherson, Ruth
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Biochemistry and Molecular Biology 2014
Предметы:
Patient-Oriented and Epidemiological Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617143/
https://ncbi.nlm.nih.gov/pubmed/25225679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P052522
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