Disruption of tumor suppressor gene Hint1 leads to remodeling of the lipid metabolic phenotype of mouse liver

A lipidomic and metabolomic investigation of serum and liver from mice was performed to gain insight into the tumor suppressor gene Hint1. A major reprogramming of lipid homeostasis was found in both serum and liver of Hint1-null (Hint(−/−)) mice, with significant changes in the levels of many lipid...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Beyoğlu, Diren, Krausz, Kristopher W., Martin, Juliette, Maurhofer, Olivier, Dorow, Juliane, Ceglarek, Uta, Gonzalez, Frank J., Dufour, Jean-François, Idle, Jeffrey R.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2014
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617133/
https://ncbi.nlm.nih.gov/pubmed/25193995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M050682
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