Afatinib in Treatment-Naive Patients With EGFR-Mutated Lung Adenocarcinoma With Brain Metastasis: A Case Series

Tyrosine kinase inhibitors (TKIs) of epidermal growth factor receptor (EGFR) were previously the standard first-line treatments for lung cancers with activating EGFR mutations. The first-generation reversible EGFR TKIs, gefitinib and erlotinib, demonstrated substantial efficacy in the treatment of b...

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Bibliographische Detailangaben
Veröffentlicht in:Medicine (Baltimore)
Hauptverfasser: Li, Shih-Hong, Hsieh, Meng-Heng, Fang, Yueh-Fu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer Health 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4616807/
https://ncbi.nlm.nih.gov/pubmed/26469914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000001739
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