Identification and characterization of VEGF-A–responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Vascular endothelial growth factor A (VEGF-A) is upregulated during hypoxia and is the major regulator of angiogenesis. VEGF-A expression has also been found to recruit myeloid cells to ischemic tissues where they contribute to angiogenesis. This study investigates the mechanisms underlying neutroph...

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Udgivet i:Blood
Main Authors: Massena, Sara, Christoffersson, Gustaf, Vågesjö, Evelina, Seignez, Cédric, Gustafsson, Karin, Binet, François, Herrera Hidalgo, Carmen, Giraud, Antoine, Lomei, Jalal, Weström, Simone, Shibuya, Masabumi, Claesson-Welsh, Lena, Gerwins, Pär, Welsh, Michael, Kreuger, Johan, Phillipson, Mia
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2015
Fag:
Phagocytes, Granulocytes, and Myelopoiesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4616235/
https://ncbi.nlm.nih.gov/pubmed/26286848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-631572
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