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Metformin Attenuates Testosterone-Induced Prostatic Hyperplasia in Rats: A Pharmacological Perspective

Benign prostatic hyperplasia (BPH) is uncontrolled proliferation of prostate tissue. Metformin, a widely prescribed anti-diabetic agent, possesses anticancer activity through induction of apoptotic signaling and cell cycle arrest. This study aimed to investigate the protective effect of metformin ag...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mosli, Hala H., Esmat, Ahmed, Atawia, Reem T., Shoieb, Sherif M., Mosli, Hisham A., Abdel-Naim, Ashraf B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4616049/
https://ncbi.nlm.nih.gov/pubmed/26492952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15639
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