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miR-214 promotes osteoclastogenesis by targeting Pten/PI3k/Akt pathway

microRNA is necessary for osteoclast differentiation, function and survival. It has been reported that miR-199/214 cluster plays important roles in vertebrate skeletal development and miR-214 inhibits osteoblast function by targeting ATF4. Here, we show that miR-214 is up-regulated during osteoclast...

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Détails bibliographiques
Publié dans:RNA Biol
Auteurs principaux: Zhao, Chenyang, Sun, Weijia, Zhang, Pengfei, Ling, Shukuan, Li, Yuheng, Zhao, Dingsheng, Peng, Jiang, Wang, Aiyuan, Li, Qi, Song, Jinping, Wang, Cheng, Xu, Xiaolong, Xu, Zi, Zhong, Guohui, Han, Bingxing, Chang, Yan-Zhong, Li, Yingxian
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615895/
https://ncbi.nlm.nih.gov/pubmed/25826666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1017205
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