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Mechanisms of blood homeostasis: lineage tracking and a neutral model of cell populations in rhesus macaques

BACKGROUND: How a potentially diverse population of hematopoietic stem cells (HSCs) differentiates and proliferates to supply more than 10(11) mature blood cells every day in humans remains a key biological question. We investigated this process by quantitatively analyzing the clonal structure of pe...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Goyal, Sidhartha, Kim, Sanggu, Chen, Irvin SY, Chou, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615871/
https://ncbi.nlm.nih.gov/pubmed/26486451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0191-8
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