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Detrimental effect of post Status Epilepticus treatment with ROCK inhibitor Y-27632 in a pilocarpine model of temporal lobe epilepsy

Temporal lobe epilepsy (TLE) is the most common type of epilepsy in adults where 20–30% of the patients are refractory to currently available anti-epileptic drugs. The RhoA/Rho-kinase signaling pathway activation has been involved in inflammatory responses, neurite outgrowth and neuronal death under...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Kourdougli, Nazim, Varpula, Saara, Chazal, Genevieve, Rivera, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615811/
https://ncbi.nlm.nih.gov/pubmed/26557054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00413
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