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Proneness of TLR5 deficient mice to develop colitis is microbiota dependent

Alterations in the gut microbiota have been implicated to play a role in potentiating inflammatory bowel diseases in both humans and mice. Mice lacking the flagellin receptor, toll-like receptor 5 (TLR5), are prone to develop spontaneous gut inflammation, but are significantly protected when treated...

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Détails bibliographiques
Publié dans:Gut Microbes
Auteurs principaux: Singh, Vishal, Yeoh, Beng San, Carvalho, Frederic, Gewirtz, Andrew T, Vijay-Kumar, Matam
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615783/
https://ncbi.nlm.nih.gov/pubmed/26067589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490976.2015.1060390
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