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Comprehensive silencing of target-sharing microRNAs is a mechanism for SIRT1 overexpression in cancer
Overexpression of SIRT1 is frequently observed in various types of cancers, suggesting its potential role in malignancies. However, the molecular basis of how SIRT1 is elevated in cancer is less understood. Here we show that cancer-related SIRT1 overexpression is due to evasion of Sirt1 mRNA from re...
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| Publicado no: | RNA Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615778/ https://ncbi.nlm.nih.gov/pubmed/25483038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.32093 |
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