Phase II Evaluation of Dalantercept, a Soluble Recombinant Activin Receptor-Like Kinase 1 (ALK1) Receptor Fusion Protein, for the Treatment of Recurrent or Persistent Endometrial Cancer: An NRG Oncology/Gynecologic Oncology Group Study 0229N

OBJECTIVE: This two-stage phase II study assessed activity of single agent dalantercept in patients with recurrent/persistent endometrial carcinoma (EMC). METHODS: Eligible patients had persistent/recurrent EMC after 1–2 prior cytotoxic regimens, measurable disease (RECIST 1.1), and GOG performance...

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Detalhes bibliográficos
Publicado no:Gynecol Oncol
Main Authors: Makker, Vicky, Filiaci, Virginia L., Chen, Lee-may, Darus, Christopher J., Kendrick, James E., Sutton, Gregory, Moxley, Katherine, Aghajanian, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615687/
https://ncbi.nlm.nih.gov/pubmed/25888978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2015.04.006
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