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Structural determinants for alternative splicing regulation of the MAPT pre-mRNA
Alternative splicing at the MAPT gene exon 10 yields similar levels of the 3R and 4R tau protein isoforms.(1) The presence of mutations, particularly in exon 10 and intron 10–11, changes the quantity of tau isoforms. Domination each of the isoform yields tau protein aggregation and frontotemporal de...
में बचाया:
| में प्रकाशित: | RNA Biol |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Taylor & Francis
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615681/ https://ncbi.nlm.nih.gov/pubmed/25826665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1017214 |
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