Chronic glutamate treatment selectively modulates AMPA RNA editing and ADAR expression and activity in primary cortical neurons

Adenosine-to-inosine RNA editing is a post-transcriptional process, catalyzed by ADAR enzymes, with an important role in diversifying the number of proteins derived from a single gene. In neurons, editing of ionotropic AMPA glutamate receptors has been shown to be altered under several experimental...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Bonini, Daniela, Filippini, Alice, La Via, Luca, Fiorentini, Chiara, Fumagalli, Fabio, Colombi, Marina, Barbon, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615659/
https://ncbi.nlm.nih.gov/pubmed/25625181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1008365
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