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Chronic glutamate treatment selectively modulates AMPA RNA editing and ADAR expression and activity in primary cortical neurons

Adenosine-to-inosine RNA editing is a post-transcriptional process, catalyzed by ADAR enzymes, with an important role in diversifying the number of proteins derived from a single gene. In neurons, editing of ionotropic AMPA glutamate receptors has been shown to be altered under several experimental...

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Bibliografische gegevens
Gepubliceerd in:RNA Biol
Hoofdauteurs: Bonini, Daniela, Filippini, Alice, La Via, Luca, Fiorentini, Chiara, Fumagalli, Fabio, Colombi, Marina, Barbon, Alessandro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615659/
https://ncbi.nlm.nih.gov/pubmed/25625181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1008365
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