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Genome-wide Survey of Runs of Homozygosity Identifies Recessive Loci for Bone Mineral Density in Caucasian and Chinese Populations

Runs of homozygosity (ROHs), in which both parental alleles are identical, have been proposed to have recessive effects on multiple human complex diseases. Osteoporosis is a common complex disease characterized by low bone mineral density (BMD), which is highly heritable. And recessive loci that con...

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Bibliografiset tiedot
Julkaisussa:J Bone Miner Res
Päätekijät: Yang, Tie-Lin, Guo, Yan, Zhang, Ji-Gang, Xu, Chao, Tian, Qing, Deng, Hong-Wen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615523/
https://ncbi.nlm.nih.gov/pubmed/25983029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2558
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