Differentiation of embryonic stem cells into insulin-producing cells promoted by Nkx2.2 gene transfer

AIM: To investigate the ability of a genetically altered embryonic stem (ES) cell line to generate insulin-producing cells in vitro following transfer of the Nkx2.2 gene. METHODS: Hamster Nkx2.2 genes were transferred into mouse ES cells. Parental and Nkx2.2-transfected ES cells were initiated towar...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Shiroi, Akira, Ueda, Shigehiko, Ouji, Yukiteru, Saito, Ko, Moriya, Kei, Sugie, Yuko, Fukui, Hiroshi, Ishizaka, Shigeaki, Yoshikawa, Masahide
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2005
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615436/
https://ncbi.nlm.nih.gov/pubmed/16015683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i27.4161
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