MC1R diversity in Northern Island Melanesia has not been constrained by strong purifying selection and cannot explain pigmentation phenotype variation in the region

BACKGROUND: Variation in human skin pigmentation evolved in response to the selective pressure of ultra-violet radiation (UVR). Selection to maintain darker skin in high UVR environments is expected to constrain pigmentation phenotype and variation in pigmentation loci. Consistent with this hypothes...

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Veröffentlicht in:BMC Genet
Hauptverfasser: Norton, Heather L., Werren, Elizabeth, Friedlaender, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615358/
https://ncbi.nlm.nih.gov/pubmed/26482799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-015-0277-x
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