The survival motor neuron gene smn-1 interacts with the U2AF large subunit gene uaf-1 to regulate Caenorhabditis elegans lifespan and motor functions

Spinal muscular atrophy (SMA), the most frequent human congenital motor neuron degenerative disease, is caused by loss-of-function mutations in the highly conserved survival motor neuron gene SMN1. Mutations in SMN could affect several molecular processes, among which aberrant pre-mRNA splicing caus...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Gao, Xiaoyang, Teng, Yanling, Luo, Jintao, Huang, Liange, Li, Min, Zhang, Zhuohua, Ma, Yong-Chao, Ma, Long
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615316/
https://ncbi.nlm.nih.gov/pubmed/25483032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.36100
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