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Periodontal inflammation and alveolar bone loss induced by Aggregatibacter actinomycetemcomitans is attenuated in sphingosine kinase 1-deficient mice
BACKGROUND AND OBJECTIVE: Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid, which is generated by activation of sphingosine kinase (SK) 1 and/or 2 in most mammalian cells with various stimuli, including the oral pathogen Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans). S1P...
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| Veröffentlicht in: | J Periodontal Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615256/ https://ncbi.nlm.nih.gov/pubmed/25900155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jre.12276 |
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