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Breakdown of Epithelial Barrier Integrity and Overdrive Activation of Alveolar Epithelial Cells in the Pathogenesis of Acute Respiratory Distress Syndrome and Lung Fibrosis

Individual alveolar epithelial cells (AECs) collaboratively form a tight barrier between atmosphere and fluid-filled tissue to enable normal gas exchange. The tight junctions of AECs provide intercellular sealing and are integral to the maintenance of the AEC barrier integrity. Disruption and failur...

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Detalles Bibliográficos
Publicado en:Biomed Res Int
Main Authors: Yanagi, Shigehisa, Tsubouchi, Hironobu, Miura, Ayako, Matsumoto, Nobuhiro, Nakazato, Masamitsu
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615219/
https://ncbi.nlm.nih.gov/pubmed/26523279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/573210
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