Detection of HER2 Amplification in Breast Carcinomas: Comparison of Multiplex Ligation-Dependent Probe Amplification (MLPA) and Fluorescence In Situ Hybridization (FISH) combined with Automated Spot Counting

In this study the detection of HER2 gene amplification was evaluated using Fluorescence In Situ Hybridization (FISH; PathVysion) in comparison with Multiplex Ligation-dependent Probe Amplification (MLPA), a PCR based technique. These two methods were evaluated on a series of 46 formalin fixed paraff...

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Publicado no:Cell Oncol
Main Authors: Moerland, Elna, van Hezik, Rens L. H. P. M., van der Aa, Toine C. J. M., van Beek, Mike W. P. M., van den Brule, Adriaan J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615166/
https://ncbi.nlm.nih.gov/pubmed/16988470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2006/741586
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