Transient association of MCM complex proteins with the nuclear matrix during initiation of mammalian DNA replication

The minichromosome maintenance complex (MCM2-7) is the putative DNA helicase in eukaryotes, and essential for DNA replication. By applying serial extractions to mammalian cells synchronized by release from quiescence, we reveal dynamic changes to the sub-nuclear compartmentalization of MCM2 as cells...

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Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Hesketh, Emma L, Knight, John RP, Wilson, Rosemary HC, Chong, James PJ, Coverley, Dawn
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615129/
https://ncbi.nlm.nih.gov/pubmed/25659032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.980647
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